BDBM581993 WO2023287730, Compound P171-2.1

SMILES C[C@@H](Nc1nc2nccn2c2cc(ccc12)C1=CCOCC1)c1cccc(c1C)C(F)(F)F

InChI Key InChIKey=XANKWZIZJRMOSR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 581993   

LigandPNGBDBM581993(WO2023287730, Compound P171-2.1)
Affinity DataIC50: 15nMAssay Description:Reaction buffer was prepared with 10 mM HEPES 7.4, 150 mM NaCl, 5 mM MgCl2, 1 mM DTT, 0.05% BSA, 0.0025% NP40, and 0.5% DMSO. Recombinant KRAS G12C p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2023
Entry Details
WIPO WO2023287730