BDBM581991 WO2023287730, Compound P170-2.4

SMILES COCC12CC(C1)(C2)C(=O)N1Cc2c(C1)n1c(C)nnc1nc2N[C@H](C)c1cc(N)cc(c1)C(F)(F)F

InChI Key InChIKey=GHNNWALBGVHKLM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 581991   

LigandPNGBDBM581991(WO2023287730, Compound P170-2.4)
Affinity DataIC50: 263nMAssay Description:Reaction buffer was prepared with 10 mM HEPES 7.4, 150 mM NaCl, 5 mM MgCl2, 1 mM DTT, 0.05% BSA, 0.0025% NP40, and 0.5% DMSO. Recombinant KRAS G12C p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2023
Entry Details
WIPO WO2023287730