BDBM581985 WO2023287730, Compound P165-2.5
SMILES C[C@@H](Nc1nc2nnc(C)n2c2CN(Cc12)C(=O)C12CC(C1)C2)c1cccc(c1)C(F)(F)F
InChI Key InChIKey=FDCPVWBSLDUVRD-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 581985
Affinity DataIC50: 263nMAssay Description:Reaction buffer was prepared with 10 mM HEPES 7.4, 150 mM NaCl, 5 mM MgCl2, 1 mM DTT, 0.05% BSA, 0.0025% NP40, and 0.5% DMSO. Recombinant KRAS G12C p...More data for this Ligand-Target Pair