BDBM581981 WO2023287730, Compound P161-2.1

SMILES COc1cc2c(N[C@H](C)c3cc(N)cc(c3)C(F)(F)F)nn3c(C)nnc3c2cc1OC

InChI Key InChIKey=HLPVSDJEFOCCLE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 581981   

LigandPNGBDBM581981(WO2023287730, Compound P161-2.1)
Affinity DataIC50: 263nMAssay Description:Reaction buffer was prepared with 10 mM HEPES 7.4, 150 mM NaCl, 5 mM MgCl2, 1 mM DTT, 0.05% BSA, 0.0025% NP40, and 0.5% DMSO. Recombinant KRAS G12C p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2023
Entry Details
WIPO WO2023287730