BDBM581302 (2S)-2-({5-[2-(2,4-diamino-6-oxo- 1,6-dihydropyrimidin-5- yl)acetamido]-3-methylpyridin-2- yl}formamido)pentanedioic acid::US11504368, Example 20

SMILES Cc1cc(NC(=O)Cc2c(N)nc(N)[nH]c2=O)cnc1C(=O)N[C@@H](CCC(O)=O)C(O)=O

InChI Key InChIKey=NYRWPFRWINKGPS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 581302   

TargetBifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial(Human)
Thomas Helledays Stiftelse FÖR Medicinsk Forskning

US Patent
LigandPNGBDBM581302(US11504368, Example 20 | (2S)-2-({5-[2-(2,4-diamin...)
Affinity DataIC50: 913nMAssay Description:To determine the IC50 value of a compound, an 11-concentration dose-response curve with 3-fold difference in concentration between assay points was g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
Go to US Patent