BDBM581076 US11504364, Compound 14

SMILES FC1(F)C[C@@H](C#N)N(C1)C(=O)CNC(=O)c1ccnc2ccc(\C=C\c3ccccc3)cc12

InChI Key InChIKey=HHYDXFLUGOASPW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 581076   

TargetProlyl endopeptidase FAP(Human)
Praxis Biotech

US Patent
LigandPNGBDBM581076(US11504364, Compound 14)
Affinity DataIC50: 1.00E+4nMAssay Description:FAPα enzymatic exopeptidase (dipeptidase) activity assay. To assay baseline FAPa enzymatic exopeptidase activity, 40 ng of recombinant human FAP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
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TargetDipeptidyl peptidase 9(Human)
Praxis Biotech

US Patent
LigandPNGBDBM581076(US11504364, Compound 14)
Affinity DataIC50: 1.00E+4nMAssay Description:DPP9 enzymatic activity assay. To assay baseline dipeptidyl peptidase 9 (DPP9) activity, 40 ng of recombinant human DPP9 (rhDPP9) (R&S system, #5419-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 4(Human)
Praxis Biotech

US Patent
LigandPNGBDBM581076(US11504364, Compound 14)
Affinity DataIC50: 1.00E+3nMAssay Description:DPPIV enzymatic activity assay. To assay baseline dipeptidyl peptidase-4 (DPPIV) activity, 40 ng of recombinant human DPPIV (rhDPPIV) (R&S system, #1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
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TargetPresequence protease, mitochondrial(Human)
Praxis Biotech

US Patent
LigandPNGBDBM581076(US11504364, Compound 14)
Affinity DataIC50: 1.00E+3nMAssay Description:PREP enzymatic activity assay. To assay baseline prolyl endopeptidase (PREP) activity, 20 ng of recombinant human PREP (rhPREP) (R&S system, #4308-SE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
Go to US Patent