BDBM581059 US11492375, Example 1121

SMILES CN1[C@H]2CCCC=CCOc3ccc(C[C@H](N(C)C2=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CSCC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N2CCCC[C@@H]2C(=O)N[C@@H](CC(O)=O)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CN)C(=O)N[C@@H](CCC(O)=O)C(=O)N2C[C@H](O)C[C@H]2C(=O)N[C@@H](Cc2c[nH]c4ccccc24)C(=O)N[C@@H](CCN)C(=O)N[C@@H](Cc2cn(CC(O)=O)c4ccccc24)C1=O)C(=O)NCC(N)=O)cc3

InChI Key InChIKey=AXFPDGWRXYYFMG-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 581059   

TargetProgrammed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E](Human)
Bristol-Myers Squibb

US Patent

LigandBDBM581059(US11492375, Example 1121)Copy SMILESCopy InChI

Affinity DataIC50: 1.05E+3nMAssay Description:The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
1/20/2023
Entry Details
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