BDBM581008 US11492367, Compound 2

SMILES CNc1ncnc2c(cnn12)C1OC2COP(O)(=O)OC3C(O)C(COP(O)(=O)OC2C1O)OC3n1cnc2c1nc(N)[nH]c2=O

InChI Key InChIKey=YUDMGIMMEPNTTB-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 581008   

TargetStimulator of interferon genes protein(Human)
Janssen Biotech

US Patent
LigandPNGBDBM581008(US11492367, Compound 2)
Affinity DataIC50: 5.67E+4nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′->5′)-monophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
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TargetStimulator of interferon genes protein(Human)
Janssen Biotech

US Patent
LigandPNGBDBM581008(US11492367, Compound 2)
Affinity DataKd:  120nMAssay Description:Compounds were analyzed on an S200 biacore SPR instrument (GE Healthcare). E. coli produced truncated STING protein was immobilized on a series S str...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
Go to US Patent