BDBM580930 (S)-5-(6-morpholino-4-((tetrahydrofuran-3- yl)sulfonyl)pyridin-2-yl)pyrimidin-2-amine::US11492348, Compound 142a

SMILES Nc1ncc(cn1)-c1cc(cc(n1)N1CCOCC1)S(=O)(=O)[C@H]1CCOC1

InChI Key InChIKey=XNGARQQVWZXOKC-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 580930   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Neuropore Therapies

US Patent

LigandBDBM580930(US11492348, Compound 142a | (S)-5-(6-morpholino-4-...)Copy SMILESCopy InChI

Affinity DataIC50: 5.70nMAssay Description:Quantification of ATP to ADP conversion as a measure of PI3Kα activity. Active PI3Kα (Life Technologies), in the presence or absence of PI3...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
1/20/2023
Entry Details
Copy BDB DOIUS Patent

Copy reaction URL