BDBM580774 US11492346, Example 119::US20250122183, Example 001

SMILES COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Cc3cc[nH]n3)cc(OC)c12

InChI Key InChIKey=VLWGGJDZAWVEAF-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 580774   

TargetHistone acetyltransferase KAT6A(Human)
Pfizer

US Patent
LigandPNGBDBM580774(US11492346, Example 119 | US20250122183, Example 0...)
Affinity DataKi:  0.400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2025
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT6A [507-778](Human)
Pfizer

US Patent
LigandPNGBDBM580774(US11492346, Example 119 | US20250122183, Example 0...)
Affinity DataKi:  13nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compound stocks 3-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT6A [507-778](Human)
Pfizer

US Patent
LigandPNGBDBM580774(US11492346, Example 119 | US20250122183, Example 0...)
Affinity DataKi:  21nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compound stocks 3-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
Go to US Patent

LigandPNGBDBM580774(US11492346, Example 119 | US20250122183, Example 0...)
Affinity DataKi:  37nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2025
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT7/Peregrin(Human)
Pfizer

US Patent
LigandPNGBDBM580774(US11492346, Example 119 | US20250122183, Example 0...)
Affinity DataKi:  37.7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2025
Entry Details
Go to US Patent

LigandPNGBDBM580774(US11492346, Example 119 | US20250122183, Example 0...)
Affinity DataKi:  131nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2025
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT5(Human)
Pfizer

US Patent
LigandPNGBDBM580774(US11492346, Example 119 | US20250122183, Example 0...)
Affinity DataKi:  441nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2025
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT8(Human)
Pfizer

US Patent
LigandPNGBDBM580774(US11492346, Example 119 | US20250122183, Example 0...)
Affinity DataKi:  455nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2025
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT7(Human)
Pfizer

US Patent
LigandPNGBDBM580774(US11492346, Example 119 | US20250122183, Example 0...)
Affinity DataKi:  650nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compound stocks 3-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
Go to US Patent