BDBM580553 5-(2-ethoxy-3-pyridyl)-3-methyl-N-[(5-methyl- 1,2,4-oxadiazol-3-yl)methyl]-1-[1- methylpropyl]pyrazolo[4,3-b]pyridin-7-amine, enantiomer 2::US11491140, Example 128

SMILES CCOc1ncccc1-c1cc(NCc2noc(C)n2)c2n(nc(C)c2n1)[C@@H](C)CC

InChI Key InChIKey=XOIXJVILDWTHEL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 580553   

LigandPNGBDBM580553(US11491140, Example 128 | 5-(2-ethoxy-3-pyridyl)-3...)
Affinity DataIC50: 1.20nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
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LigandPNGBDBM580553(US11491140, Example 128 | 5-(2-ethoxy-3-pyridyl)-3...)
Affinity DataIC50: 0.260nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
Go to US Patent

LigandPNGBDBM580553(US11491140, Example 128 | 5-(2-ethoxy-3-pyridyl)-3...)
Affinity DataIC50: 4.10nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
Go to US Patent