BDBM580550 5-(2-ethoxy-3-pyridyl)-N-[(5-methoxy-3- pyridyl)methyl]-3-methyl-1-[1- methylpropyl]pyrazolo[4,3-b]pyridin-7-amine, enantiomer 2::US11491140, Example 125

SMILES CCOc1ncccc1-c1cc(NCc2cncc(OC)c2)c2n(nc(C)c2n1)[C@H](C)CC

InChI Key InChIKey=SYWOKLNWWYOPHL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 580550   

LigandPNGBDBM580550(US11491140, Example 125 | 5-(2-ethoxy-3-pyridyl)-N...)
Affinity DataIC50: 1nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
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Date in BDB:
1/20/2023
Entry Details
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LigandPNGBDBM580550(US11491140, Example 125 | 5-(2-ethoxy-3-pyridyl)-N...)
Affinity DataIC50: 0.320nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
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LigandPNGBDBM580550(US11491140, Example 125 | 5-(2-ethoxy-3-pyridyl)-N...)
Affinity DataIC50: 4.30nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
Go to US Patent