BDBM580542 5-(2-ethoxy-3-pyridyl)-3-methyl-1-[1- methylpropyl]-N-(1H-pyrazol-3- ylmethyl)pyrazolo[4,3-b]pyridin-7-amine, enantiomer 2::US11491140, Example 120

SMILES CCOc1ncccc1-c1cc(NCc2cc[nH]n2)c2n(nc(C)c2n1)[C@@H](C)CC

InChI Key InChIKey=MSYXYAZMFHMJKN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 580542   

LigandPNGBDBM580542(US11491140, Example 120 | 5-(2-ethoxy-3-pyridyl)-3...)
Affinity DataIC50: 4.60nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
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LigandPNGBDBM580542(US11491140, Example 120 | 5-(2-ethoxy-3-pyridyl)-3...)
Affinity DataIC50: 0.270nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
Go to US Patent

LigandPNGBDBM580542(US11491140, Example 120 | 5-(2-ethoxy-3-pyridyl)-3...)
Affinity DataIC50: 7.60nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
Go to US Patent