BDBM580481 US11491158, Cmpd 13

SMILES Cn1cc(-c2cccc(NS(=O)(=O)c3cccc(Cl)c3)c2F)c2c(N)ncnc12

InChI Key InChIKey=CJVVPJALBXRULW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 580481   

TargetEukaryotic translation initiation factor 2-alpha kinase 3 [540-1115](Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM580481(US11491158, Cmpd 13)
Affinity DataIC50: 16nMAssay Description:The biochemical activity of compounds was determined by incubation with PERK recombinant enzyme (cytoplasmic domain corresponding to residues 540-111...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
Go to US Patent