BDBM580308 N-[[6-(3-cyclohexylpropanoyl)- 6-azaspiro[2.5]octan-2- yl]methyl]-1,3- dihydropyrrolo[3,4-c]pyridine-2- carboxamide::US11485745, Example 197

SMILES O=C(CCC1CCCCC1)N1CCC2(CC2CNC(=O)N2Cc3ccncc3C2)CC1

InChI Key InChIKey=GDCCPZPQHRFXOL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 580308   

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM580308(US11485745, Example 197 | N-[[6-(3-cyclohexylpropa...)
Affinity DataIC50: 11.1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
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