BDBM580119 US11485745, Example 3::tert-butyl 2- [(imidazo[1,2- a]pyrimidine-6- carbonylamino)methyl]- 8-azaspiro[2.5]octane- 8-carboxylate

SMILES CC(C)(C)OC(=O)N1CCC2(CC2CNC(=O)c2cnc3cccn3c2)CC1

InChI Key InChIKey=ZOWFVCVHKOVRHE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 580119   

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM580119(US11485745, Example 3 | tert-butyl 2- [(imidazo[1,...)
Affinity DataIC50: 8.96nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
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