BDBM579534 US11484525, Compound DD-79-I

SMILES C[C@@H](Cc1ccsc1)NC(=O)NC[C@H](Cc1ccnc(O)c1)N(C)C

InChI Key InChIKey=MHGSNGKSHQNLLY-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 579534   

TargetMu-type opioid receptor [N127C](Human)
University of California

US Patent
LigandPNGBDBM579534(US11484525, Compound DD-79-I)
Affinity DataKi:  210nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
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TargetKappa-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM579534(US11484525, Compound DD-79-I)
Affinity DataKi:  1.20E+3nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

TargetDelta-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM579534(US11484525, Compound DD-79-I)
Affinity DataKi:  4.10E+3nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent