BDBM579503 US11484525, Compound DD-81

SMILES CN(C)C(CNC(=S)NCCc1ccsc1)Cc1ccc(O)cc1

InChI Key InChIKey=JNRNKLNRVDTXHL-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 579503   

TargetMu-type opioid receptor [N127C](Human)
University of California

US Patent
LigandPNGBDBM579503(US11484525, Compound DD-81)
Affinity DataKi:  29nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
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TargetDelta-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM579503(US11484525, Compound DD-81)
Affinity DataKi:  70nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM579503(US11484525, Compound DD-81)
Affinity DataKi:  86nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent