BDBM579492 US11484525, Compound BD-127-DS::US11484525, Compound BD-127LS

SMILES C[C@@H](Cc1ccsc1)NC(=O)NCC(Cc1ccccc1)N(C)C

InChI Key InChIKey=LGUNAZMQJSOQTG-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 579492   

TargetMu-type opioid receptor [N127C](Human)
University of California

US Patent
LigandPNGBDBM579492(US11484525, Compound BD-127-DS | US11484525, Compo...)
Affinity DataKi:  140nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM579492(US11484525, Compound BD-127-DS | US11484525, Compo...)
Affinity DataKi:  1.00E+3nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

TargetMu-type opioid receptor [N127C](Human)
University of California

US Patent
LigandPNGBDBM579492(US11484525, Compound BD-127-DS | US11484525, Compo...)
Affinity DataKi:  2.40E+3nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

TargetDelta-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM579492(US11484525, Compound BD-127-DS | US11484525, Compo...)
Affinity DataKi:  2.80E+3nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM579492(US11484525, Compound BD-127-DS | US11484525, Compo...)
Affinity DataKi:  3.10E+3nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

TargetDelta-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM579492(US11484525, Compound BD-127-DS | US11484525, Compo...)
Affinity DataKi:  1.10E+4nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent