BDBM579113 1-(6-(2-fluoropropan-2-yl)pyridin-2-yl)-2-isopropyl-6-((4-(4-methylpiperazin-1-yl)phenyl)amino)-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one::US11479555, Example 13

SMILES CC(C)n1n(-c2cccc(n2)C(C)(C)F)c2nc(Nc3ccc(cc3)N3CCN(C)CC3)ncc2c1=O

InChI Key InChIKey=XDUMWKMZNQAGRY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 579113   

TargetWee1-like protein kinase(Human)
Newave Pharmaceutical

US Patent
LigandPNGBDBM579113(1-(6-(2-fluoropropan-2-yl)pyridin-2-yl)-2-isopropy...)
Affinity DataIC50: 1.5nMAssay Description:In determination of the Weel kinase activity, a synthetic peptide, Poly(Lys,Tyr) Hydrobromide (Lys:Tyr (4:1)) bought from Sigma was used as the subst...More data for this Ligand-Target Pair
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Date in BDB:
12/30/2022
Entry Details
US Patent