BDBM578759 US11479550, Example 8-13(2)

SMILES COCCNC(=O)c1ccc2n(cc(C)c2c1)[C@H](C)C(=O)Nc1cc(CC2=NCC(C)=C2)ccc1CCCC(O)=O

InChI Key InChIKey=KZFAFFUQMWDFOM-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 578759   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM578759(US11479550, Example 8-13(2))
Affinity DataIC50: 6.30nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
US Patent

TargetProstaglandin E2 receptor EP3 subtype(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM578759(US11479550, Example 8-13(2))
Affinity DataKi:  1.60E+3nMAssay Description:To each well of a 96 well plate, 10 μL of a medium (dimethyl sulfoxide; DMSO) which had been 10-fold diluted with an assay buffer solution (10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
US Patent