BDBM578730 US11479543, Compound I-42

SMILES CN1c2cc(Br)ccc2OC[C@H](NC(=O)n2cc(Cc3cccnc3F)cn2)C1=O

InChI Key InChIKey=WRJMWDJPNRTILL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 578730   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM578730(US11479543, Compound I-42)
Affinity DataIC50: 18.2nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent