BDBM578722 US11479543, Compound I-33

SMILES CN1c2cc(ccc2OC[C@H](NC(=O)n2cc(Cc3cccc(F)n3)cn2)C1=O)C#CC1(O)CCOCC1

InChI Key InChIKey=YNJAUDKKFLBNPF-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 578722   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent

LigandBDBM578722(US11479543, Compound I-33)Copy SMILESCopy InChI

Affinity DataIC50: 17.1nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/30/2022
Entry Details
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