BDBM578501 US11479539, Compound 20

SMILES COC1(CC(C)(C)C(=O)C(=C1)C#N)c1cccc(n1)C(F)(F)F

InChI Key InChIKey=GPAKOEKAWCXKMC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 578501   

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578501(US11479539, Compound 20)
Affinity DataEC50:  126nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent