BDBM578489 US11479539, Compound 8

SMILES COC1CN(C1)c1cccc(n1)C1(CC(C)(C)C(=O)C(=C1)C#N)OC

InChI Key InChIKey=ZEXRYGJGRPZYJR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 578489   

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578489(US11479539, Compound 8)
Affinity DataEC50:  186nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent