BDBM578487 US11479539, Compound 6

SMILES CC1(C)CC(O)(C=C(C#N)C1=O)c1ncccc1C(F)F

InChI Key InChIKey=AJPWOFCZSCXLFZ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 578487   

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578487(US11479539, Compound 6)
Affinity DataEC50: >1.00E+4nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent