BDBM578433 (R) N-(4-(1H-pyrazol-4-yl)phenyl)-2-((2-methoxyethyl)amino)-2-(3-methoxyphenyl)acetamide::US11479533, Example 58

SMILES COCCN[C@@H](C(=O)Nc1ccc(cc1)-c1cn[nH]c1)c1cccc(OC)c1

InChI Key InChIKey=AXHOMFNSCRXCJW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 578433   

TargetRho-associated protein kinase 2 [1-552](Human)
Kadmon

US Patent
LigandPNGBDBM578433((R) N-(4-(1H-pyrazol-4-yl)phenyl)-2-((2-methoxyeth...)
Affinity DataIC50: 12nMAssay Description:Compounds activities were measured by Z'-lyte kinase kit (ThermoFisher Scientific). The percent inhibition rate was calculated by normalizing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

TargetRho-associated protein kinase 1 [1-535](Human)
Kadmon

US Patent
LigandPNGBDBM578433((R) N-(4-(1H-pyrazol-4-yl)phenyl)-2-((2-methoxyeth...)
Affinity DataIC50: 57nMAssay Description:Compounds activities were measured by Z'-lyte kinase kit (ThermoFisher Scientific). The percent inhibition rate was calculated by normalizing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent