BDBM578415 N-(4-(1H-pyrazol-4-yl)phenyl)-2-(ethylamino)-2-(p-tolyl)acetamide::US11479533, Example 11::US11479533, Example 21

SMILES CNC(C(=O)Nc1ccc(cc1)-c1cn[nH]c1)c1ccc(C)cc1

InChI Key InChIKey=SVXRWXHNUCIQTG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 578415   

TargetRho-associated protein kinase 2 [1-552](Human)
Kadmon

US Patent
LigandPNGBDBM578415(US11479533, Example 11 | US11479533, Example 21 | ...)
Affinity DataIC50: 4nMAssay Description:Compounds activities were measured by Z'-lyte kinase kit (ThermoFisher Scientific). The percent inhibition rate was calculated by normalizing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

TargetRho-associated protein kinase 2 [1-552](Human)
Kadmon

US Patent
LigandPNGBDBM578415(US11479533, Example 11 | US11479533, Example 21 | ...)
Affinity DataIC50: 3.10nMAssay Description:Compounds activities were measured by Z'-lyte kinase kit (ThermoFisher Scientific). The percent inhibition rate was calculated by normalizing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent