BDBM5781 5-benzoyl-4-(pentyloxy)-1H-pyrazolo[3,4-b]pyridine::SQ-67563 Analog 11d::pyrazolo[3,4-b]pyridine deriv.

SMILES CCCCCOc1c(cnc2[nH]ncc12)C(=O)c1ccccc1

InChI Key InChIKey=JZHOKFOEFIRVGO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5781   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bristol-Myers Squibb

LigandPNGBDBM5781(5-benzoyl-4-(pentyloxy)-1H-pyrazolo[3,4-b]pyridine...)
Affinity DataIC50: 240nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2005
Entry Details Article
PubMed
LigandPNGBDBM5781(5-benzoyl-4-(pentyloxy)-1H-pyrazolo[3,4-b]pyridine...)
Affinity DataIC50: 310nMAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2005
Entry Details Article
PubMed