BDBM577548 US11472838, Compound Ref. 22

SMILES CCCC[C@H](NC(=O)[C@H](CC\C=C\C(=O)OC)NC(=O)[C@@H](CC(O)=O)NC(C)=O)C(=O)N[C@@H](CCCC)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N1CCC[C@H]1C(O)=O

InChI Key InChIKey=CAZYOEQAOTWMPB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 577548   

TargetCoagulation factor XIII A chain(Human)
Zedira

US Patent
LigandPNGBDBM577548(US11472838, Compound Ref. 22)
Affinity DataIC50: 110nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

LigandPNGBDBM577548(US11472838, Compound Ref. 22)
Affinity DataIC50: 2.92E+3nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandPNGBDBM577548(US11472838, Compound Ref. 22)
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant coagulation factor XIIIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed