BDBM577123 10-(4-Chloro-5-fluoro-2-methylphenyl)-8-cyclopropyl-3,4,7,8-tetrahydro-2H-pyrano[2',3':4,5]pyrrolo[1,2-a]pyrazin-9(6H)-one::US11472805, Example 29

SMILES Cc1cc(Cl)c(F)cc1-c1c2OCCCc2n2CCN(C3CC3)C(=O)c12

InChI Key InChIKey=XEPASQPUIOGOCW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 577123   

LigandPNGBDBM577123(US11472805, Example 29 | 10-(4-Chloro-5-fluoro-2-m...)
Affinity DataIC50: 1nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
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LigandPNGBDBM577123(US11472805, Example 29 | 10-(4-Chloro-5-fluoro-2-m...)
In Depth
Date in BDB:
12/24/2022
Entry Details
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LigandPNGBDBM577123(US11472805, Example 29 | 10-(4-Chloro-5-fluoro-2-m...)
Affinity DataIC50: 2.45nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
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LigandPNGBDBM577123(US11472805, Example 29 | 10-(4-Chloro-5-fluoro-2-m...)
Affinity DataIC50: 12.7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent