BDBM577101 4-(8-Cyclopropyl-9-oxo-3,4,6,7,8,9-hexahydro-2H-pyrano[2′,3′:4,5]pyrrolo[1,2-a]pyrazin-10-yl)-2-fluoro-5-methylbenzonitrile ::US11472805, Example 16

SMILES Cc1cc(C#N)c(F)cc1-c1c2OCCCc2n2CCN(C3CC3)C(=O)c12

InChI Key InChIKey=FNRUBUFCNWKZEI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 577101   

LigandPNGBDBM577101(US11472805, Example 16 | 4-(8-Cyclopropyl-9-oxo-3,...)
Affinity DataIC50: 1.57nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
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LigandPNGBDBM577101(US11472805, Example 16 | 4-(8-Cyclopropyl-9-oxo-3,...)
Affinity DataIC50: 1.78nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
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LigandPNGBDBM577101(US11472805, Example 16 | 4-(8-Cyclopropyl-9-oxo-3,...)
Affinity DataIC50: 15.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
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LigandPNGBDBM577101(US11472805, Example 16 | 4-(8-Cyclopropyl-9-oxo-3,...)
Affinity DataIC50: 45.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent