BDBM577091 10-(4-Chloro-3-fluorophenyl)-8-cyclopropyl-7,8-dihydropyrrolo[1,2-a:4,5-b′]dipyrazin-9(6H)-one ::US11472805, Example 8

SMILES Fc1cc(ccc1Cl)-c1c2C(=O)N(CCn2c2nccnc12)C1CC1

InChI Key InChIKey=PYJYVNMGHSGIDT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 577091   

LigandPNGBDBM577091(US11472805, Example 8 | 10-(4-Chloro-3-fluoropheny...)
Affinity DataIC50: 1.19nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
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LigandPNGBDBM577091(US11472805, Example 8 | 10-(4-Chloro-3-fluoropheny...)
Affinity DataIC50: 1.27nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
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LigandPNGBDBM577091(US11472805, Example 8 | 10-(4-Chloro-3-fluoropheny...)
Affinity DataIC50: 13.9nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
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LigandPNGBDBM577091(US11472805, Example 8 | 10-(4-Chloro-3-fluoropheny...)
Affinity DataIC50: 88.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent