BDBM576859 4-(1-(2-Chloro-4- ((((1S,3S)-3- hydroxycyclohexyl)amino) methyl)phenyl)-1H- pyrazol-4-yl)-2((1- (methylsulfonyl)piperidin- 4-yl)amino)pyrimidine- 5-carbonitrile::US11472791, Example 181

SMILES CS(=O)(=O)N1CCC(CC1)Nc1ncc(C#N)c(n1)-c1cnn(c1)-c1ccc(CN[C@H]2CCC[C@H](O)C2)cc1Cl

InChI Key InChIKey=BPYVTOOLNIAAPT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 576859   

LigandPNGBDBM576859(4-(1-(2-Chloro-4- ((((1S,3S)-3- hydroxycyclohexy...)
Affinity DataIC50: 50nMAssay Description:CDK2/Cyclin E1 enzyme activity assays utilize full-length human CDK2 co-expressed as N-terminal GST-tagged protein with FLAG-Cyclin E1 in a baculovir...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2022
Entry Details
US Patent