BDBM576807 N-(1- (Ethylsulfonyl)piperidin- 4-yl)-4-(1-(2-methyl-4- (((methyl- d3)amino)methyl)phenyl)- 1H-pyrazol-4-yl)-5- (trifluoromethyl)pyrimidin- 2-amine::US11472791, Example 129

SMILES CCS(=O)(=O)N1CCC(CC1)Nc1ncc(c(n1)-c1cnn(c1)-c1ccc(CNC)cc1C)C(F)(F)F

InChI Key InChIKey=SXAOTWWLRKSXGJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 576807   

LigandPNGBDBM576807(US11472791, Example 129 | N-(1- (Ethylsulfonyl)pi...)
Affinity DataIC50: 50nMAssay Description:CDK2/Cyclin E1 enzyme activity assays utilize full-length human CDK2 co-expressed as N-terminal GST-tagged protein with FLAG-Cyclin E1 in a baculovir...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2022
Entry Details
US Patent