BDBM576802 5-Chloro-4-(1-(2-chloro-4- ((methylamino)methyl) phenyl)-1H-pyrazol-4-yl)- N-(1- (methylsulfonyl)piperidin- 4-yl)pyrimidin-2-amine::US11472791, Example 124::US11472791, Example 134

SMILES CNCc1ccc(c(Cl)c1)-n1cc(cn1)-c1nc(NC2CCN(CC2)S(C)(=O)=O)ncc1Cl

InChI Key InChIKey=ASGKCUMTPHCICM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 576802   

LigandPNGBDBM576802(US11472791, Example 124 | 5-Chloro-4-(1-(2-chloro-...)
Affinity DataIC50: 50nMAssay Description:CDK2/Cyclin E1 enzyme activity assays utilize full-length human CDK2 co-expressed as N-terminal GST-tagged protein with FLAG-Cyclin E1 in a baculovir...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2022
Entry Details
US Patent

LigandPNGBDBM576802(US11472791, Example 124 | 5-Chloro-4-(1-(2-chloro-...)
Affinity DataIC50: 50nMAssay Description:CDK2/Cyclin E1 enzyme activity assays utilize full-length human CDK2 co-expressed as N-terminal GST-tagged protein with FLAG-Cyclin E1 in a baculovir...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2022
Entry Details
US Patent