BDBM576794 4-(1-(2-Chloro-4- ((methylamino)methyl) phenyl)-1H-pyrazol-4-yl)-2- (((3R,4S)-3-fluoro-1- (methylsulfonyl)piperidin- 4-yl)amino)pyrimidine- 5-carbonitrile::US11472791, Example 116::US11472791, Example 143

SMILES CNCc1ccc(c(Cl)c1)-n1cc(cn1)-c1nc(N[C@H]2CCN(C[C@H]2F)S(C)(=O)=O)ncc1C#N

InChI Key InChIKey=KYXNZMIBWRNFLA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 576794   

LigandPNGBDBM576794(US11472791, Example 116 | 4-(1-(2-Chloro-4- ((meth...)
Affinity DataIC50: 50nMAssay Description:CDK2/Cyclin E1 enzyme activity assays utilize full-length human CDK2 co-expressed as N-terminal GST-tagged protein with FLAG-Cyclin E1 in a baculovir...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2022
Entry Details
US Patent

LigandPNGBDBM576794(US11472791, Example 116 | 4-(1-(2-Chloro-4- ((meth...)
Affinity DataIC50: 50nMAssay Description:CDK2/Cyclin E1 enzyme activity assays utilize full-length human CDK2 co-expressed as N-terminal GST-tagged protein with FLAG-Cyclin E1 in a baculovir...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2022
Entry Details
US Patent