BDBM576714 US11472791, Example 128::US11472791, Example 41

SMILES CNCc1ccc(c(C)c1)-n1cc(cn1)-c1nc(NC2CCN(CC2)S(C)(=O)=O)ncc1C(F)(F)F

InChI Key InChIKey=CPNJWSSSCAOSPW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 576714   

LigandPNGBDBM576714(US11472791, Example 41 | US11472791, Example 128)
Affinity DataIC50: 50nMAssay Description:CDK2/Cyclin E1 enzyme activity assays utilize full-length human CDK2 co-expressed as N-terminal GST-tagged protein with FLAG-Cyclin E1 in a baculovir...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2022
Entry Details
US Patent

LigandPNGBDBM576714(US11472791, Example 41 | US11472791, Example 128)
Affinity DataIC50: 50nMAssay Description:CDK2/Cyclin E1 enzyme activity assays utilize full-length human CDK2 co-expressed as N-terminal GST-tagged protein with FLAG-Cyclin E1 in a baculovir...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2022
Entry Details
US Patent