BDBM576624 US11472776, Example 13::US20240158357, Example 13

SMILES COc1ccc(cn1)-n1c(nc2ccsc2c1=O)-c1ccc(NC(C)=O)cc1

InChI Key InChIKey=ROZOKBPFZRVMIT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 576624   

LigandPNGBDBM576624(US11472776, Example 13 | US20240158357, Example 13)
Affinity DataIC50: 1.36E+4nMAssay Description:AlphaLisa Assay (ALA) was used as a primary screen for identifying compounds that inhibit tau oligomer formation. It is a bead based assay that only ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2022
Entry Details
Go to US Patent

TargetMicrotubule-associated protein tau(Human)
Oligomerix

US Patent
LigandPNGBDBM576624(US11472776, Example 13 | US20240158357, Example 13)
Affinity DataIC50: 4.53E+3nMAssay Description:AlphaLisa Assay (ALA) was used as a primary screen for identifying compounds that inhibit tau oligomer formation. It is a bead based assay that only ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
Go to US Patent

TargetMicrotubule-associated protein tau(Human)
Oligomerix

US Patent
LigandPNGBDBM576624(US11472776, Example 13 | US20240158357, Example 13)
Affinity DataIC50: 1.70E+3nMAssay Description:Confirmatory Assay (CONFA) used as a secondary screen for confirming the mechanism of action of compounds identified as hits using the ALA assay. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
Go to US Patent