BDBM576551 (E)-2-(4-(((4-((2-(aminomethyl)-3- fluoroallyl)oxy)phenyl)sulfonyl) methyl)bicyclo[2.2.2]octan-1- yl)isothiazolidine 1,1-dioxide::US11472769, Compound 82

SMILES NC\C(COc1ccc(cc1)S(=O)(=O)CC12CCC(CC1)(CC2)N1CCCS1(=O)=O)=C/F

InChI Key InChIKey=WLUTWHGQNAPIHT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 576551   

TargetAmine oxidase [flavin-containing] A(Human)
Eccogene (Shanghai)

US Patent
LigandPNGBDBM576551(US11472769, Compound 82 | (E)-2-(4-(((4-((2-(amino...)
Affinity DataIC50: 3.00E+4nMAssay Description:Amine oxidase activity of recombinant hSSAO, hMAO-A, and hMAO-B isoforms are measured using the MAO-Glo assay kit (Promega, V1402). Ten nL test compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2022
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Eccogene (Shanghai)

US Patent
LigandPNGBDBM576551(US11472769, Compound 82 | (E)-2-(4-(((4-((2-(amino...)
Affinity DataIC50: 3.00E+4nMAssay Description:Amine oxidase activity of recombinant hSSAO, hMAO-A, and hMAO-B isoforms are measured using the MAO-Glo assay kit (Promega, V1402). Ten nL test compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2022
Entry Details
Go to US Patent

TargetAmine oxidase [copper-containing] 2(Human)
Eccogene (Shanghai)

US Patent
LigandPNGBDBM576551(US11472769, Compound 82 | (E)-2-(4-(((4-((2-(amino...)
Affinity DataIC50: 20nMAssay Description:Amine oxidase activity of recombinant hSSAO, hMAO-A, and hMAO-B isoforms are measured using the MAO-Glo assay kit (Promega, V1402). Ten nL test compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2022
Entry Details
Go to US Patent