BDBM576472 (E)-3-fluoro-2-((4-(((4- methyltetrahydro-2H-pyran-4- yl)methyl)sulfonyl)phenoxy)methyl) prop-2-en-1-amine::US11472769, Compound 5

SMILES CC1(CS(=O)(=O)c2ccc(OC\C(CN)=C\F)cc2)CCOCC1

InChI Key InChIKey=JAYAAKNKQJNPFY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 576472   

TargetAmine oxidase [flavin-containing] A(Human)
Eccogene (Shanghai)

US Patent
LigandPNGBDBM576472(US11472769, Compound 5 | (E)-3-fluoro-2-((4-(((4- ...)
Affinity DataIC50: 3.00E+4nMAssay Description:Amine oxidase activity of recombinant hSSAO, hMAO-A, and hMAO-B isoforms are measured using the MAO-Glo assay kit (Promega, V1402). Ten nL test compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2022
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Eccogene (Shanghai)

US Patent
LigandPNGBDBM576472(US11472769, Compound 5 | (E)-3-fluoro-2-((4-(((4- ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Amine oxidase activity of recombinant hSSAO, hMAO-A, and hMAO-B isoforms are measured using the MAO-Glo assay kit (Promega, V1402). Ten nL test compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2022
Entry Details
Go to US Patent

TargetAmine oxidase [copper-containing] 2(Human)
Eccogene (Shanghai)

US Patent
LigandPNGBDBM576472(US11472769, Compound 5 | (E)-3-fluoro-2-((4-(((4- ...)
Affinity DataIC50: 20nMAssay Description:Amine oxidase activity of recombinant hSSAO, hMAO-A, and hMAO-B isoforms are measured using the MAO-Glo assay kit (Promega, V1402). Ten nL test compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2022
Entry Details
Go to US Patent