BDBM576471 (R,E)-2-((4-(((5,5-dimethyl-1,4- dioxan-2- yl)methyl)sulfonyl)phenoxy)methyl)- 3-fluoroprop-2-en-1-amine::US11472769, Compound 4

SMILES CC1(C)CO[C@@H](CS(=O)(=O)c2ccc(OC\C(CN)=C\F)cc2)CO1

InChI Key InChIKey=QGIQVPBFAKZFRQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 576471   

TargetAmine oxidase [flavin-containing] A(Human)
Eccogene (Shanghai)

US Patent
LigandPNGBDBM576471(US11472769, Compound 4 | (R,E)-2-((4-(((5,5-dimeth...)
Affinity DataIC50: 3.00E+4nMAssay Description:Amine oxidase activity of recombinant hSSAO, hMAO-A, and hMAO-B isoforms are measured using the MAO-Glo assay kit (Promega, V1402). Ten nL test compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2022
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Eccogene (Shanghai)

US Patent
LigandPNGBDBM576471(US11472769, Compound 4 | (R,E)-2-((4-(((5,5-dimeth...)
Affinity DataIC50: 2.00E+4nMAssay Description:Amine oxidase activity of recombinant hSSAO, hMAO-A, and hMAO-B isoforms are measured using the MAO-Glo assay kit (Promega, V1402). Ten nL test compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2022
Entry Details
Go to US Patent

TargetAmine oxidase [copper-containing] 2(Human)
Eccogene (Shanghai)

US Patent
LigandPNGBDBM576471(US11472769, Compound 4 | (R,E)-2-((4-(((5,5-dimeth...)
Affinity DataIC50: 60nMAssay Description:Amine oxidase activity of recombinant hSSAO, hMAO-A, and hMAO-B isoforms are measured using the MAO-Glo assay kit (Promega, V1402). Ten nL test compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2022
Entry Details
Go to US Patent