BDBM576407 4-(3,5-di ethyl-1H-pyrazol-4-yl)-7-fluoro-1,3-benzothiazole::WO2022112919, Example 12

SMILES Cc1n[nH]c(C)c1-c1ccc(F)c2scnc12

InChI Key InChIKey=HKFYHWTVCYRWBR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 576407   

TargetTransthyretin(Human)
Pfizer

WIPO
LigandPNGBDBM576407(4-(3,5-di ethyl-1H-pyrazol-4-yl)-7-fluoro-1,3-benz...)
Affinity DataEC50:  37nMAssay Description:TTR SPA binding assays were performed in a final volume of 60 mI containing 100 ng human TTR (biotinylated recombinant protein) coupled to 25 pg SPA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022112919