BDBM576406 WO2022112919, Example 11

SMILES COc1ccc(-c2c(C)n[nH]c2C)c2ncsc12

InChI Key InChIKey=MKJVGLRMNYMXOX-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 576406   

TargetTransthyretin(Human)
Pfizer

WIPO
LigandPNGBDBM576406(WO2022112919, Example 11)
Affinity DataEC50:  36nMAssay Description:TTR SPA binding assays were performed in a final volume of 60 mI containing 100 ng human TTR (biotinylated recombinant protein) coupled to 25 pg SPA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022112919