BDBM576392 N-[6-(5-chloro-1,3-benzoxazol-2-yl)spiro[3.3]heptan-2-yl]-5-(cyclopropylmethylsulfinyl)furan-2-carboxamide::WO2022112207, Example 19-b

SMILES Clc1ccc2oc(nc2c1)[C@H]1C[C@]2(C[C@@H](C2)NC(=O)c2ccc(o2)[S@](=O)CC2CC2)C1

InChI Key InChIKey=IGBLCXVNXCXYHT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 576392   

TargetLarge envelope protein(HBV-D)
F. Hoffmann-La Roche

WIPO
LigandPNGBDBM576392(N-[6-(5-chloro-1,3-benzoxazol-2-yl)spiro[3.3]hepta...)
Affinity DataIC50: 71nMAssay Description:Detailed procedures regarding primary human hepatocyte (PHH) HBV natural infection assay are described as below. One tube of frozen PHH (10 million c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022112207

TargetExternal core antigen(HBVgbn)
F. Hoffmann-La Roche

WIPO
LigandPNGBDBM576392(N-[6-(5-chloro-1,3-benzoxazol-2-yl)spiro[3.3]hepta...)
Affinity DataIC50: 53nMAssay Description:Detailed procedures regarding primary human hepatocyte (PHH) HBV natural infection assay are described as below. One tube of frozen PHH (10 million c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022112207