BDBM576343 WO2022112205, Example 1::WO2022112205, Example 9

SMILES CS(=O)(=O)c1ccc(o1)C(=O)NC12CC(C1)(C2)c1nc2cc(Cl)ccc2o1

InChI Key InChIKey=VALPDIWUWVCNES-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 576343   

TargetLarge envelope protein(HBV-D)
F. Hoffmann-La Roche

WIPO
LigandPNGBDBM576343(WO2022112205, Example 1 | WO2022112205, Example 9)
Affinity DataIC50: 2.17E+3nMAssay Description: Detailed procedures regarding primary human hepatocyte (PHH) HBV natural infection assay are described as below. One tube of frozen PHH (10 million ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022112205

TargetExternal core antigen(HBVgbn)
F. Hoffmann-La Roche

WIPO
LigandPNGBDBM576343(WO2022112205, Example 1 | WO2022112205, Example 9)
Affinity DataIC50: 1.77E+3nMAssay Description: Detailed procedures regarding primary human hepatocyte (PHH) HBV natural infection assay are described as below. One tube of frozen PHH (10 million ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022112205

TargetLarge envelope protein(HBV-D)
F. Hoffmann-La Roche

WIPO
LigandPNGBDBM576343(WO2022112205, Example 1 | WO2022112205, Example 9)
Affinity DataIC50: 9.64E+3nMAssay Description: Detailed procedures regarding primary human hepatocyte (PHH) HBV natural infection assay are described as below. One tube of frozen PHH (10 million ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022112205

TargetExternal core antigen(HBVgbn)
F. Hoffmann-La Roche

WIPO
LigandPNGBDBM576343(WO2022112205, Example 1 | WO2022112205, Example 9)
Affinity DataIC50: 5.37E+3nMAssay Description: Detailed procedures regarding primary human hepatocyte (PHH) HBV natural infection assay are described as below. One tube of frozen PHH (10 million ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022112205