BDBM576218 WO2022094012, Example 21A

SMILES CCN1[C@H](C)c2ccc(OC)c(c2)-c2cn3ccnc3c(OCCCOC[C@@H](CCC(F)(F)F)NC1=O)n2

InChI Key InChIKey=IPKAQWXJVXPKAE-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 576218   

TargetOrexin receptor type 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM576218(WO2022094012, Example 21A)
Affinity DataEC50:  20nMAssay Description: In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022094012