BDBM5762 3-(4-Methoxyphenyl)-5-(butylcarbamoyl)aminoindeno[1,2-c]pyrazol-4-one::3-butyl-1-[3-(4-methoxyphenyl)-4-oxo-2H,4H-indeno[1,2-c]pyrazol-5-yl]urea::Indenopyrazole 11h

SMILES CCCCNC(=O)Nc1cccc2-c3[nH]nc(c3C(=O)c12)-c1ccc(OC)cc1

InChI Key InChIKey=JDTZDVYNBUXATI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5762   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bristol-Myers Squibb

LigandPNGBDBM5762(3-butyl-1-[3-(4-methoxyphenyl)-4-oxo-2H,4H-indeno[...)
Affinity DataIC50: 84nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Bristol-Myers Squibb

LigandPNGBDBM5762(3-butyl-1-[3-(4-methoxyphenyl)-4-oxo-2H,4H-indeno[...)
Affinity DataIC50: 780nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2005
Entry Details Article
PubMed