BDBM576172 WO2022056448, Compound 43

SMILES Cc1c2C(=O)N3CCc4ccc(cc4C3)[C@@H](CC(O)=O)c3cnc4n(CC\C=C/CCc5ccc(n2C)c1c5)nnc4c3C

InChI Key InChIKey=IJDQXSQWJLQCRL-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 576172   

TargetKelch-like ECH-associated protein 1/Nuclear factor erythroid 2-related factor 2(Human)
Sanofi

WIPO

LigandBDBM576172(WO2022056448, Compound 43)Copy SMILESCopy InChI

Affinity DataIC50: 0.200nMAssay Description:In a first step, the Keapl /compound complex was prepared by addition of 100 nL of the compound by ECHO 555, followed by 5 pL aliquots of 2x Keapl. T...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/14/2022
Entry Details
Copy Entry DOIWIPO WO2022056448

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