BDBM576061 4-(1-(3-methoxybenzyl)-2- methyl-1H-imidazo[4,5-b] pyridin-6-yl)-2-methyl-1,6- dihydro-7H-pyrrolo[2,3-c] pyridin-7-one::US11466034, Example 16

SMILES COc1cccc(Cn2c(C)nc3ncc(cc23)-c2c[nH]c(=O)c3[nH]c(C)cc23)c1

InChI Key InChIKey=YNVUJMHQSSJDPC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 576061   

TargetBromodomain-containing protein 4 [44-167](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM576061(4-(1-(3-methoxybenzyl)-2- methyl-1H-imidazo[4,5-b]...)
Affinity DataIC50: 200nMAssay Description:The assays of BRD4 (D1) and BRD4 (D2) were conducted in a 384-well polystyrene plate. The test compounds were first serially diluted in DMSO and the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [349-460](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM576061(4-(1-(3-methoxybenzyl)-2- methyl-1H-imidazo[4,5-b]...)
Affinity DataIC50: 100nMAssay Description:The assays of BRD4 (D1) and BRD4 (D2) were conducted in a 384-well polystyrene plate. The test compounds were first serially diluted in DMSO and the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
Go to US Patent